Uses This product is used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut. Simethicone helps break up gas bubbles in the gut. How to use Simethicone-80 Tablet, Chewable Take this product by mouth, usually 2-4 times a day after meals and at bedtime, or as directed by your doctor. Chew the tablets thoroughly before swallowing. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist. If you are self-treating with simethicone, the usual maximum amount for adults is 500 milligrams daily. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.